To understand the effects of Nattokinase,  it is important to have knowledge of its history and the initial production of natto. In Japan in 1083, it is speculated that Yoshiie Minamoto, a famous samurai accidentally discovered natto. While on a battle campaign, his army was attacked while they boiled soybeans to feed their horses. Due to the circumstances, the troops quickly packed the soybeans in straw baskets. A few days later, the troops ate the fermented soybeans and found the taste agreeable. The rice straw was the perfect place for the soybeans to ferment.  For over a thousand years, the Japanese people have enjoyed fermented soybeans which they called natto and have discovered its health benefits.

It has been well documented that the Japanese have fewer health problems associated with cardiovascular disease than other people of the world. Researchers have discovered the curative properties of Nattokinase relating to cardiovascular health and its ability to dissolve blood clots.
In 1980 Dr. Sumi, a Japanese research scientist, took a small portion of natto and placed it in the plate that contained the artificial thrombus (fibrin)  and noted that the natto slowly dissolved the thrombus within 18 hours. His extensive research confirms that Nattokinase is an effective natural product to dissolve blood clots as well as preventing clots from forming.

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